Tiny pacemaker can be implanted into the heart through blood vessels without surgery 12/13/2013 - 00:00 Pacemaker surgery typically requires a doctor to make an incision above a patient’s heart, dig a cavity into which they can implant the heartbeat-regulating device, and then connect the pulse generator to wires delivered through a vein near the collarbone. Such surgery could soon be completely unnecessary. Instead, doctors could employ miniaturized wireless pacemakers that can be delivered into the heart through a major vein in the thigh.On Monday, doctors in Austria implanted one such device into a patient—the first participant in a human trial of what device-manufacturer Medtronicsays is the smallest pacemaker in the world. The device is 24 millimeters long and 0.75 cubic centimeters in volume—a tenth the size of a conventional pacemaker. Earlier this year, another device manufacturer, St. Jude Medical, bought a startup called Nanostim that makes another tiny pacemaker, and St. Jude is offering it to patients in Europe. This device is 41 millimeters long and one cubic centimeter in volume.Doctors can implant such pacemakers into the heart through blood vessels, via an incision in the thigh. They use steerable, flexible tubes called catheters to push the pacemakers through a large vein.