New ingredient invented could be added to food in order to trick your brain into feeling full

12/14/2014 - 00:00

By Sam Wong -

In its first tests in humans, researchers at Imperial College London and the University of Glasgow found that the ingredient is effective at preventing weight gain in overweight volunteers.

The ingredient contains propionate, which stimulates the gut to release hormones that act on the brain to reduce hunger. Propionate is produced naturally when dietary fibre is fermented by microbes in the gut, but the new ingredient, called inulin-propionate ester (IPE), provides much larger quantities of propionate than people can acquire with a normal diet.


Ref:  E.S. Chambers et al. 'Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults.' Gut, 2014. DOI: 10.1136/gutjnl-2014-307913