Researchers at Brigham and Women's Hospital (BWH) and Carnegie Mellon University have introduced a unique micro-robotic technique to assemble the components of complex materials, the foundation of tissue engineering and 3D printing.
Described in the Jan. 28, 2014, issue of Nature Communications, the research was conducted by Savas Tasoglu, PhD, MS, research fellow in the BWH Division of Renal Medicine, and Utkan Demirci, PhD, MS, associate professor of Medicine in the Division of Biomedical Engineering, part of the BWH Department of Medicine, in collaboration with Eric Diller, PhD, MS, and Metin Sitti, PhD, MS, professor in the Department of Mechanical Engineering, Carnegie Mellon University.
Tissue engineering and 3D printing have become vitally important to the future of medicine for many reasons. The shortage of available organs for transplantation, for example, leaves many patients on lengthy waiting lists for life-saving treatment. Being able to engineer organs using a patient's own cells can not only alleviate this shortage, but also address issues related to rejection of donated organs. Developing therapies and testing drugs using current preclinical models have limitations in reliability and predictability. Tissue engineering provides a more practical means for researchers to study cell behavior, such as cancer cell resistance to therapy, and test new drugs or combinations of drugs to treat many diseases.
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