By Florian Frisch -
Parkinson’s disease affects neurons in the Substantia nigra brain region – their mitochondrial activity ceases and the cells die. Researchers at the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) show that supplying D-lactate or glycolate, two products of the gene DJ-1, can stop and even counteract this process: Adding the substances to cultured HeLa cells and to cells of the nematode C. elegans restored the activity of mitochondria and prevented the degeneration of neurons.
READ MORE ON MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS
Yusuke Toyoda, Cihan Erkut, Francisco Pan-Montojo, Sebastian Boland, Martin P. Stewart, Daniel J. Müller, Wolfgang Wurst, Anthony Hyman und Teymuras V. Kurzchalia:
Products of the Parkinson’s-disease-related glyxolase DJ-1, D-lactate and glycolate, support mitochondrial membrane potential and neuronal survival
Researchers find yogurt based substances that 'stop and even counteract' Parkinson's disease
