A functional synthetic immune organ has been created - Can be controlled to produce antibodies

By Anne Ju -

Cornell engineers have created a functional, synthetic immune organ that produces antibodies and can be controlled in the lab, completely separate from a living organism. The engineered organ has implications for everything from rapid production of immune therapies to new frontiers in cancer or infectious disease research.

The immune organoid was created in the lab of Ankur Singh, assistant professor of mechanical and aerospace engineering, who applies engineering principles to the study and manipulation of the human immune system.

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Ref: Ex vivo Engineered Immune Organoids for Controlled Germinal Center Reactions. Biomaterials (2015) | DOI:10.1016/j.biomaterials.2015.06.002